Selection of an M184V mutation in the cerebrospinal fluid of a treatment-naive HIV-infected individual starting darunavir-based therapy.

نویسندگان

  • Marion Cornelissen
  • Nicole K T Back
  • David M Burger
  • Petra Blom
  • Peter Portegies
  • Jan M Prins
  • Marc van der Valk
چکیده

Here, we describe a newly diagnosed HIV-1-infected patient, in whom shortly after the initiation of a darunavir-based regimen, the HIV-1 virus exclusively mutated in the cerebrospinal fluid (CSF), leading to an increase in CSF HIV-1 RNA load and neurological complaints.

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عنوان ژورنال:
  • Antiviral therapy

دوره 16 6  شماره 

صفحات  -

تاریخ انتشار 2011